APP Stress Lab: Lexiscan Reaction

This medical simulation scenario centers on a 49-year-old female with multiple comorbidities preparing for a laparoscopic hysterectomy. She presents for preoperative risk stratification after a history of syncope in 2021 with prior negative cardiac workup. Recently, she reports atypical chest pain during walking and worsening dyspnea. During a Lexiscan stress test, she experienced significant bradycardia and hypotension requiring both pharmacological and non-pharmacological interventions. This scenario offers an expert-level training opportunity to recognize, manage, and stabilize adverse reactions during pharmacologic stress testing in complex patients.